logo
Wrong email address or username
Wrong email address or username
Incorrect verification code
Antitumor Drug Resistance (Handbook of Experimental Pharmacology) - Brian W. Fox, M. Fox, M. Fox, N.K. Ahmed, B. Barlogie, W.T. Beck, A. Begleiter, A.K. Belousova, J.R. Bertino, J.M. Boyle, J. Brennand, C.T. Caskey, T.A. Connors, B. Drewinko, H. Fuji, G.J. Goldenberg, J.F. Henderson, B.T. Hill, J.A. Houghton, P.J. Houghton, M.M. Ip, J.G. McVi
Add cover
Antitumor Drug Resistance (Handbook of Experimental Pharmacology)
by: (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author) (author)
The study of tumour resistance to anticancer drugs has been the subject of many publications since the initial discovery of the phenomenon by J. H. Burchenal and colleagues in 1950. Many papers have been published since then reporting development of resistance to most of the well-known anticancer... show more
The study of tumour resistance to anticancer drugs has been the subject of many publications since the initial discovery of the phenomenon by J. H. Burchenal and colleagues in 1950. Many papers have been published since then reporting development of resistance to most of the well-known anticancer agents in many different animal tumour systems, both in vivo and in vitro. Many different mechanisms of resistance have been described, and it is clear that the tumour cell has a wide diversity of options in overcoming the cell-killing activity of these agents. Definition of the magnitude of the phenomenon in the clinic is, however, much more problematical, and it is with this in mind that the initial chapter, seeks to out­ line the problem as the clinicians see it. It appears that the phenomenon of true resistance to a drug, as the biochemist would recognise it, is an important cause of the failure which clinicians experience in treating the disease. The extent of the contribution of this phenomenon to the failure of treatment cannot easily be evaluated at the present time, but it is hoped that the development and application of new and more sophisticated techniques for the analysis of cellular sub­ populations may help to give a more exact estimate and to shed some light on the causes of failure of many of the present therapeutic techniques.
show less
Format: Hardcover
ISBN: 9783540130697 (3540130691)
ASIN: 3540130691
Publisher: Springer
Pages no: 738
Edition language: English
Bookstores:
Books by Brian W. Fox
Books by D.M. Tidd
Books by K.D. Tew
Books by P.S. Schein
Books by H. Fuji
Books by B. Drewinko
Books by J. Brennand
Books by A. Begleiter
Books by David P Houghton
Books by Z.B. Hill
Books by G. Goldenberg
Books by J. Gordon McVie
Books by Eugene T. Connors
Books by B. Barlogie
Books by Malcolm J. L. Uren
Books by L. A Belousova
Books by C.J. Henderson
Books by C. Thomas Caskey
Books by Tony J. Watson
Books by N. U Ahmed
Books by Timothy J. Houghton
Books by Anthony J. Bertino
Books by A.J. Boyle
Books by M. Tisdale
Books by Theresa M. Moore
Books by Kim M. Fox
Books by Kim M. Fox
Books by Margot M. Ip
Books by Peter J. Whitehouse
Books by W.H. Beck
Books by Michael D. Scott
Books by David A. Welch
Share this Book
Need help?