Daisy Hubbard, a genetic researcher in a prestigious Boston lab, is driven to find a cure for the rare genetic disease that claimed the life of her younger brother. Her progress is halted, however, when her mentally unstable sister Anna is discovered missing from her California home. Daisy, fearing the worst, drops everything and flies across the country to find Anna. Once there, she is informed by the LAPD that known serial killer Roy Gaines has confessed to Anna's murder, but he will only reveal where he has hidden the body if he can lead Daisy to it himself. Daisy, teaming up with a handsome detective named Jack Makowski, follows Roy to a number of dead bodies, but none of them are Anna's. As Daisy realizes that Roy knows too much about her research, she begins to fear that Anna is a pawn in a game with much larger stakes. It will take all of Daisy's cunning and resolve to stop the killer in his tracks and to uncover his obsession with the disease she has been trying to unravel for her entire life.