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url 2019-06-19 14:04
World Sickle Cell Day

Every year on 19 June, World Sickle Cell Day is celebrated to increase public awareness about the sickle cell disease, diagnosis, and treatment methods. It was organized by the United Nation in 2008 and first time celebrated on 19 June 2009. Sickle cell disease (SCD) is a common genetic disease which affects red blood cells, and the cells become sickle-shaped which blocks the blood flow which causes pain. It has affected millions worldwide and has become a big public health issue. Read More 


Source: adiintellect.com/blog/world-sickle-cell-day
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text 2019-06-11 12:02
Stem Cell Cartilage Regeneration Market Upcoming Trends Analysis Till 2026

In cartilage regeneration, stem cells have the potential for multiple differentiation and self-replication, making it an ideal choice for use as seed cells. Growing regenerative medicine industry and increasing demand for stem cells in the development of various types of cell therapies are expected to drive growth of the market over the forecast period. Mesenchymal stem cells are the most widely applied stem cells in the field of cartilage regeneration.


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Market Dynamics


Growing osteoarthritis incidence among the global population is supporting the adoption of stem cell cartilage regeneration therapy. For instance, according to November 2017, Arthritis Foundation data findings, with the increase in global geriatric population, degenerative disease disorders such as osteoarthritis will impact at least 130 million individuals around the globe by 2050.


Furthermore, various government agencies are focusing on policies to enhance adoption of stem cell therapies, which is expected to drive growth of stem cell cartilage regeneration market in the near future. For instance, in December 2016, the 21st Century Cures Act (Cures Act) was signed into law by the U.S. FDA, thereby allowing legislation for an expedited approval path for cellular medicines designated as regenerative medicine advanced therapies (RMATs) to patients who are in need of it.


Stem Cell Cartilage Regeneration Market - Regional Insights


On the basis of region, the global stem cell cartilage regeneration market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to be the most conducive region for growth of the stem cell cartilage regeneration market over the forecast period, due to high presence of key players in the region. Key players such as Vericel Corporation, Osiris Therapeutics, among others are focusing on various growth strategies such as gaining regulatory product approvals and launching innovative stem cell based cartilage regeneration products and technologies in the market.


Stem Cell Cartilage Regeneration Market - Competitive Landscape


Key players operating in the global stem cell cartilage regeneration market include Theracell Advanced Biotechnology Ltd., Orthocell Ltd., Xintela AB, CellGenix GmbH, Merck KGaA, Osiris Therapeutics, Inc., BioTissue SA, and Vericel Corporation.


Detailed Segmentation:


Global Stem Cell Cartilage Regeneration Market, By Stem Cell Type:

Hematopoietic Stem Cells (HSCs)

Pluripotent Stem Cells (iPSC/ESCs)

Mesenchymal Stem Cells (MSCs)


Global Stem Cell Cartilage Regeneration Market, By Treatment:


Osteochondral Transplant

Autologous Chondrocyte Implantation

Stem Cell Injections


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text 2019-06-03 08:37
Personalized Cell Therapy Market Huge Growth Opportunity Trend By 2018-2026

The patient-tailored therapies for the treatment of variety of disease are known as personalized cell therapy. The personalized cell therapy is based on genomic profile, and disease prevalence/severity and the drug developed by this therapy target the patients who matches the specific disease physiopathology and/or patient characteristics.

The personalized cell therapy is mainly developed for the treatment of high unmet need disease such as cancer, also it comprises drugs for treatment of other diseases such as autoimmune disease, cardiovascular, neurologic and inflammatory disease.

Personalized cell therapy also finds application in the area of platelet transfusions, packed red cell transfusions, bone marrow transplantation and in organ transplantation.


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Personalized Cell Therapy Market Dynamics

The continuous development in science and technology sector has led to development of various novel individualized drugs, which would fuel growth of the personalized cell therapy market in the near future. Personalized cell therapy favors the accurate diagnosis of the disease and active monitoring of the treatment response and disease progression. This allows for early detection of diseases at molecular level and enables the physician to prepare the treatment regime for the specific patient requirement. This helps the patient recover at a significant pace and also helps avoid any major side effects, as individualized cell therapy is based on patient’s genomics.

Newly introduced procedures and techniques are expected to favor increase in adoption rate for personalized cell therapy in the near future. New ventures in the biologics industry are expected to be a major push for the market to grow, for instance, a high demand for biological compounds is influencing organizations to manufacture products using the biopharmaceutical process, which is further administered through injections.

Large untapped markets in emerging economies can be capitalized upon through favorable product pricing, which further can facilitate the increase in number of procedures worldwide. Also, as the manufacturing cost requirement is low in emerging economies as compare to developed countries this will help to grow the market in emerging economies such as India and China.

Key features of the study:

  • This report provides in-depth analysis of the personalized cell therapy market and provides market size (US$ Mn) and Cumulative Annual Growth Rate (CAGR) (%) for the forecast period (2017–2024)

  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market. It provides valuable insights about market drivers, restraints, opportunities, new product launches or approval, pipeline drugs, regional outlook, and competitive strategy adopted by the leading players

  • It profiles leading players in the global personalized cell therapy market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, key developments, and future plans

  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions with respect to their future product launch, market expansion, and marketing tactics

Detailed Segmentation:

  • Global Personalized Cell Therapy Market, By Applications:

    • Platelet Transfusions

    • Bone Marrow Transplantation

    • Packed Red Cell Transfusions

    • Organ Transplantation

Increased economic burden due to neurological disorders expected to fuel the growth in personalized cell therapy market

In complicated neurological disorders such as multiple sclerosis, stroke or spinal cord injuries, scientist claim that stem cells treatment may be the best option or choice of cure. Stem cells can be replaced with damaged cells or the cells, which are highly mitigated to immune responses even in the central nervous system. There are no successful clinical trials so far, as the scientists are facing hurdles in stem cell therapies, however, the use of embryonic stem cells is still a moral issue in most of the regions, obtaining adult stem cells is difficult to collect or tough to be expanded in a therapeutically sufficient amount.


Some of the major companies in personalized cell therapy market are Cytori Therapeutics Inc., Bellicum Pharmaceuticals, Inc., Saneron CCEL Therapeutics, Inc., MolMed S.p.A. and Vericel Corporation.


Click To Read More On Personalized Cell Therapy Market 

About Coherent Market Insights:
Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.

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text 2019-05-29 11:46
Single Cell Analysis Market Professional Survey Report Trends, Growth Rate, Segment And Forecasts To 2026

Single cell analysis is an emerging technology that helps sequence whole human genome at a single cell level. This particularly includes genomics, transcriptomics, proteomics, epigenomics, and metabolomics with its sensitivity improved to single cell level. In genomics, new generation methodologies such as next generation sequencing and third generation sequencing play crucial roles. The aim of single cell analysis is mainly to measure and analyze cellular heterogeneity. Single cell analysis interpret life at fundamental level and find immense applications in the field of medicine. Single cell analysis over conventional standard cell numbers sequencing method enable the discovery and investigation of unknown micro-organisms.

A study published in the Journal of Single Cell Analysis 2014, stated that a variety of technologies that are powerful and less expensive, such as Multiple Annealing And Looping-Based Amplification Cycle (MALBAC) and Multiple Displacement Amplification (MDA), find great progress in uncovering somatic mutations in human genome and detection of copy number variation. But in human single-cell genomics, Whole Genome Sequencing or Whole Exome-Sequencing (WGS or WESseq) finds great potential in clinical applications, especially in screening, diagnosis, and monitoring. It is popular in academic research because mRNA helps bridge genome structure and epigenomics modification with phenotype, reveals gene functions and regulatory network, and most importantly it is easier to perform than proteomics.


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Inclination toward single-cell technology by biologists is mainly because many samples including stem cells, immune cells, neurons, cancers, and other tissues exhibit a stochastic nature with heterogeneity factor. Conventional methods cannot provide transcriptomic profile in highly heterogeneous cell population. Even if cell population is less, single cell analysis can enable the identification of biomarkers of delicate phenotypes or disorders (e.g. cancer stem cells). In addition, this analytical technique also helps classify different cell types in different physiological and pathological conditions, in very rare events of any somatic mutation, epigenetic modification of regulatory gene expression, and its function.


Global Single Cell Analysis Market Taxonomy

The global single cell analysis market is segmented on the basis of product, types of cells, type of technique, application, and end user.

By product:Consumables (beads, microplate, reagents, assay kits, etc.), Instruments (PCR, NGS system, spectrophotometers, etc.), Automated, Manual

10x Genomics, in 2017, launched the chromium single cell V(D)J solution for profiling full length paired V(D)J transcripts from hundreds to millions of lymphocyte. It is a reagent system, which has the ability to completely identify and characterize T and B cells by single cell sequencing. This will reveal true clonality and diversity in adaptive immune system. This product will have an impact on research based single cell analysis market.

By Types of cells: Human, Animal, Microbial

By Type of technique: Mass Spectroscopy (MS), Polymerase Chain Reaction (PCR), Next-Generation Sequencing, Flow Cytometry, Microscopy,


Adoption rate of treatment options, for instance, stem cell therapy and in-vitro fertilization (IVF) is increasing significantly.

Long shelf life of single cell analysis products and consumable products is another driver for the growth of single cell analysis market.

However, high cost of instruments may have a negative impact on market growth in future.


Global Single Cell Analysis Market – Trends and Opportunity

A study by the Journal of Analytical and Bioanalytical Chemistry in 2014, stated that Inductively Coupled Plasma Mass Spectroscopy (ICP-MS) and ICP Optical Emission Spectrometry (ICP-OES) are applied using metal atoms such as nanoparticle for investigation of cell-to-cell variance or cellular uptake of drugs and other elements. Single-cell genomics find many clinical applications such as genetic diagnosis of embryo-related diseases and to study blood-borne Circulating Tumor Cells (CTCs). These applications may be further employed for diagnosis, prognosis, and treatment of cancer.

Major key players in the global single cell analysis market include 10X Genomics, Abcam Plc., Agilent Technologies, Fluxion Biosciences, Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., Bio-Techne Corporation, Bruker, Danaher Corporation, Fluidigm Corporation, GE Healthcare, and Illumina, among others.

Click to read more on Single Cell Analysis Market

About Coherent Market Insights:

Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.

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