Global Single Cell Analysis Market is anticipated to reach USD 5.9 billion in the forecast period. Single-cell analysis is the study of transcriptomics, genomics, metabolomics and proteomics at the single cell level. The analysis provides the type of examination which is helpful in various segments and it has been supported by the constant technological updates in research implements.

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Factors, such as increasing focus on personalized medicine, technological developments in single-cell analysis products, increasing research and development in the single cell analysis field, rapid progression in the healthcare segment across the globe and partnership and collaboration among key players to favor market development are likely to drive the single-cell analysis industry in forthcoming period.

On the other hand, high cost of single-cell analysis products and lack of awareness are anticipated to hinder the market growth of single cell analysis in the future. However, growth in stem cell research is likely to create lucrative opportunities for the market. Single cell analysis market is anticipated to expand at a significant CAGR in the upcoming period as the scope, product types, and its applications are increasing across the globe.

Single cell analysis industry is segmented by product type, types of cell, technique, application, end user and geography. Based on product segmentation, the single cell market comprises Consumable, and Instruments. The “Consumable” segment accounted for a prominent share in the market. It is likely to witness substantial growth in the years to come. The key factors that could be attributed to the growth of the market include existing players accepting numerous policies to boost sales and continuous demand from end users.

Based on types of cell, the single-cell analysis market could span Animal, Human, and Microbial Cells. The market could be explored based on technique as Polymerase Chain Reaction, Mass Spectroscopy, and Others. The key applications that could be explored in the single cell analysis industry include Diagnostic and Research Applications. Single cell analysis market could be explored by the end user as Biotechnology and Biopharmaceutical Companies, Academic & Research Institutes, and Others.

North America is a leading region in the market. It is likely to maintain a dominance in the forecast period owing to factors, such as the establishment of new biopharmaceutical and biotechnology products in the region. Furthermore, acceptance of gene-based analysis methods by these companies and research laboratories is increasing the regional market growth.

In addition, North America is followed by the Asia-Pacific region owing to several government initiatives undertaken to progress healthcare infrastructure, accessibility of skilled specialists to work advanced analytical instruments, and increasing healthcare spending.

Key players operating in the single cell analysis industry include Abcam Plc., 10X Genomics, Agilent Technologies, Becton, Fluxion Biosciences, Bio-Rad Laboratories, Inc., Dickinson and Company, Illumina, Danaher Corporation, Bruker, GE Healthcare, Fluidigm Corporation, and Bio-Techne Corporation, among others. The leading companies are taking up partnerships, mergers and acquisitions, and joint ventures in order to boost the inorganic growth of the industry.

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 Market Segment:

Single Cell Analysis Product Type Outlook (Revenue, USD Million, 2014 - 2025)
    • Consumables
        • Reagents
        • Assay Kits
        • Other Consumables
    • Instruments
        • Manual Instruments
        • Microscopes
        • Haemocytometers
        • Automated Instruments
        • Flowcytometers
        • Next Generation Sequencing
        • PCR Systems
        • High-content Screening System
        • Cell Microarrays
        • Automated Cell Counters

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Single cell analysis is an emerging technology that helps sequence whole human genome at a single cell level. This particularly includes genomics, transcriptomics, proteomics, epigenomics, and metabolomics with its sensitivity improved to single cell level. In genomics, new generation methodologies such as next generation sequencing and third generation sequencing play crucial roles. The aim of single cell analysis is mainly to measure and analyze cellular heterogeneity. Single cell analysis interpret life at fundamental level and find immense applications in the field of medicine. Single cell analysis over conventional standard cell numbers sequencing method enable the discovery and investigation of unknown micro-organisms.

A study published in the Journal of Single Cell Analysis 2014, stated that a variety of technologies that are powerful and less expensive, such as Multiple Annealing And Looping-Based Amplification Cycle (MALBAC) and Multiple Displacement Amplification (MDA), find great progress in uncovering somatic mutations in human genome and detection of copy number variation. But in human single-cell genomics, Whole Genome Sequencing or Whole Exome-Sequencing (WGS or WESseq) finds great potential in clinical applications, especially in screening, diagnosis, and monitoring. It is popular in academic research because mRNA helps bridge genome structure and epigenomics modification with phenotype, reveals gene functions and regulatory network, and most importantly it is easier to perform than proteomics.

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Inclination toward single-cell technology by biologists is mainly because many samples including stem cells, immune cells, neurons, cancers, and other tissues exhibit a stochastic nature with heterogeneity factor. Conventional methods cannot provide transcriptomic profile in highly heterogeneous cell population. Even if cell population is less, single cell analysis can enable the identification of biomarkers of delicate phenotypes or disorders (e.g. cancer stem cells). In addition, this analytical technique also helps classify different cell types in different physiological and pathological conditions, in very rare events of any somatic mutation, epigenetic modification of regulatory gene expression, and its function.

Global Single Cell Analysis Market Taxonomy

The global single cell analysis market is segmented on the basis of product, types of cells, type of technique, application, and end user.

By product:Consumables (beads, microplate, reagents, assay kits, etc.), Instruments (PCR, NGS system, spectrophotometers, etc.), Automated, Manual

10x Genomics, in 2017, launched the chromium single cell V(D)J solution for profiling full length paired V(D)J transcripts from hundreds to millions of lymphocyte. It is a reagent system, which has the ability to completely identify and characterize T and B cells by single cell sequencing. This will reveal true clonality and diversity in adaptive immune system. This product will have an impact on research based single cell analysis market.

By Types of cells: Human, Animal, Microbial

By Type of technique: Mass Spectroscopy (MS), Polymerase Chain Reaction (PCR), Next-Generation Sequencing, Flow Cytometry, Microscopy,

Adoption rate of treatment options, for instance, stem cell therapy and in-vitro fertilization (IVF) is increasing significantly.

Long shelf life of single cell analysis products and consumable products is another driver for the growth of single cell analysis market.

However, high cost of instruments may have a negative impact on market growth in future.

Global Single Cell Analysis Market – Trends and Opportunity

A study by the Journal of Analytical and Bioanalytical Chemistry in 2014, stated that Inductively Coupled Plasma Mass Spectroscopy (ICP-MS) and ICP Optical Emission Spectrometry (ICP-OES) are applied using metal atoms such as nanoparticle for investigation of cell-to-cell variance or cellular uptake of drugs and other elements. Single-cell genomics find many clinical applications such as genetic diagnosis of embryo-related diseases and to study blood-borne Circulating Tumor Cells (CTCs). These applications may be further employed for diagnosis, prognosis, and treatment of cancer.

Major key players in the global single cell analysis market include 10X Genomics, Abcam Plc., Agilent Technologies, Fluxion Biosciences, Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., Bio-Techne Corporation, Bruker, Danaher Corporation, Fluidigm Corporation, GE Healthcare, and Illumina, among others.

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