I am a huge fan of Calvin & Hobbes. If you have not read any of Watterson's cartoons, then you are truly missing out on a treat. The father was like my father ... Calvin and Hobbes like me and my sister ... definitely definitely worth it.
Watterson managed to do so much with Calvin and Hobbes, it's kind of amazing. As much as Schulz played with Snoopy's imagination, he totally ignored the imagination of the kids, whereas Watterson gives it life.