The global Protein Expression Market is anticipated to grow at a CAGR of 10.4% by 2025 and is expected to cross USD 3.0 billion in the forecast period. Protein expression could prove to be a complex process, since each protein requires intracellular milieu to significantly achieve secondary features. Proteins, on the other hand, may also receive certain modifications to cellular membrane to function effectively.

Protein expression industry is driven by factors such as rise in protein production, biologics production, and research. Rise in demand for biologics by manufacturers also propels the market growth in the forecast period. Increase in R&D activities, governments’ investments, effective mergers and acquisitions are also expected to drive the growth of protein expression market in the forecast period. On the other hand, prevalence of chronic diseases such as cancer, asthma, and arthritis are likely to add to the market growth. However, stringent regulations imposed by governing authorities for drug approvals are expected to hinder the market growth in the forecast period.

The protein expression industry is segmented as expression systems, product, application and geography. Product segmentation for protein expression market includes mammalian cell, yeast, insect, and prokaryotic. Prokaryotic expressions are anticipated to grow at a higher CAGR in the forthcoming period due to high revenue generating segment and increase in production capacity.

Application segment includes research, diagnostics, and therapeutics. “Therapeutic” segment is further sub-segmented into insulin, antibodies, growth factors, blood factors, enzymes, and interferons. “Therapeutic” application is expected to grow at an enormous CAGR in the forecast period owing to increase in production of biologics. The segment is also anticipated to grow rapidly in the forecast period due to rising popularity of therapeutic drugs over generic drugs. “Research” application is further anticipated to grow at a substantial CAGR in the forecast period due to increase in government funding and high accuracy.

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Geographical segmentation for protein expression industry includes North America, Latin America, Europe, Asia-Pacific, Middle East, and Africa. North American market is expected to account for a significant market share in the forthcoming period due to rise in government investment coupled with rise in biopharmaceutical and biotechnology sector as well as presence of well-defined healthcare infrastructure.

Asia-Pacific’s protein expression market is expected to grow at a positive CAGR in the upcoming period due to availability of untapped potential opportunities. Middle Eastern and African markets are anticipated to grow at a positive CAGR in the forecast period owing to improving healthcare infrastructure and increasing base of medical professionals in these areas. The key players in the protein expression industry include Agilent Technologies, Bio-Rad Laboratories Inc, Thermo Fisher Scientific Inc, New England Biolabs, Merck KGaA, Qiagen, Promega Corporation and Takara Bio Inc.

Market Segment:

Expression Systems Outlook (Revenue, USD Million; 2014 - 2025)
    • Prokaryotic expression systems
    • Mammalian cell expression systems
    • Insect cell expression systems
    • Yeast expression systems
    • Other expression systems

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Global Protein Engineering Market is anticipated to reach USD 3.09 billion by 2025. Protein engineering is a method to design novel proteins or enzymes with the intention to have functional properties. Protein engineering is primarily based on the use of recombinant DNA technology to alter the amino acid sequences in terms of affinity, solubility, activity, resistance, etc.

The factors that propel the growth of the Protein Engineering industry include increasing occurrence of lifestyle associated diseases, increasing consciousness regarding healthcare, increasing healthcare expenditure, and growing adoption of protein-based drugs. On the other hand, there are factors that may hamper the growth of the market including lack of skilled expertise, maintenance, and high price of tools as well as instruments utilized during protein engineering. Protein Engineering Market is anticipated to grow at a significant CAGR of 15.9% in the upcoming period as the scope, product types, and its applications are increasing across the globe.

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The market may be explored by product type, technology, protein type, end users, and geography. The market may be explored by product type as services and software, instruments, and reagents. The “Instruments” segment dominated the market in 2016 and is anticipated to maintain its dominance in the forecast period.

The key technologies that could be explored in the Protein Engineering industry include Irrational Protein Design, and Rational Protein Design. The “Rational Protein Design” segment dominated the market in 2016 and is anticipated to maintain its dominance by 2025 owing to highly accepted technology in the market in 2014. This huge share could be ascribed to its advantages over irrational protein design technology.

The Protein Engineering Market could be explored based on protein type as Insulin, Erythropoietin, Vaccines, Monoclonal Antibodies, Interferon, Growth hormones, Colony Stimulating factor, Coagulation Factor, Others (Follicle Stimulating Hormones, Enzyme Replacement, and Interleukins). The “Monoclonal Antibodies” segment dominated the market in 2016 and is anticipated to maintain its dominance by 2025 owing to increase in acceptance for several treatments such as autoimmune diseases, and cancer.

Protein Engineering industry could be analyzed by end user as contract research organizations, academic research institutes, and pharmaceutical & biotechnology companies. The “Pharmaceutical and Biotechnology Companies” segment dominated the market. The factors contributing to the dominant share include increase in R&D funds in the pharmaceutical segment, and technological advancements in protein engineering.

North America is anticipated to hold the major share of the Protein Engineering Market. The factors that attribute to the dominant share include growing occurrence of diseases and rising adoption of protein-based drugs in the region. The North American market is followed by Europe. On the other hand, Asia Pacific is estimated to show high growth rates in the upcoming period in the global market. In the Asia Pacific region, countries such as China and India are expected to be the fastest-growing markets.

Some of the key players that fuel the growth of the Protein Engineering industry comprise Eli Lilly and Company, Thermo Fisher Scientific Inc., Merck KGaA, Bruker Corporation, PerkinElmer Inc., Agilent Technologies, Waters Corporation, Novo Nordisk A/S, Bio-Rad Laboratories Inc., Amgen Inc., and among others. The leading companies are taking up partnerships, mergers and acquisitions, and joint ventures in order to boost the inorganic growth of the industry.

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Market Segment:

Technology Outlook (Revenue, USD Million, 2014 - 2025)
    • Rational Protein Design
    • Directed Evolution
    • Hybrid Approach

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Global Protein Ingredients Market size is expected to reach USD 48.77 billion by 2025. Protein is a macronutrient which is essential to building blocks of the human body. It is generally found in animal product and present in the other sources such as legumes and nuts. Seafood, meat, poultry, beans, grains and dairy products are the good sources of protein. The increasing awareness amongst the consumers, especially for dietary supplements and functional foods is a main factor drive the growth of market in the coming years. The market is expected to register a CAGR of 7.4% in the upcoming period as the scope, product types, and its applications are increasing across the globe.

There are two types of protein-based products are available such as animal proteins and plant proteins. The animal proteins consist of egg protein, whey protein concentrates, milk protein concentrates/ isolates whey protein hydrolysates, gelatin, whey protein isolates, casein / caseinates and others whereas the plant protein including wheat, soy protein concentrates, textured soy protein, soy protein isolates, pea, canola and others. The “soy protein concentrates” are the high consumed form of plant proteins ingredients and is projected to grow at the higher CAGR in the upcoming period due to it easily digestible and having greater fat retention capacity and higher nutritional level. Also, the soy concentrates are increasingly used in breakfast cereals, baked products, meat products and poultry products.

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Protein ingredients could be explored by application such as infant formulations, foods & beverages, personal care & cosmetics, animal feed, protein & nutritional bars, supplements & nutritional powders, pharmaceuticals, breakfast cereals, bakery & confectionery, dairy products, meat & meat products and others. The “food & beverage” industry is expected to hold the large market share in the years to come owing to the growing population, changing lifestyle of consumers and rising number of cafes & restaurants especially in the emerging countries of India and China.

The factors that play an important role in the growth of this market include increasing demand, growing population, increasing urbanization & industrialization, growing consumer inclination towards healthy food, rising concerns about animal nutrition & health, increasing demand for superior personal & health care products, increasing health consciousness among consumers and increasing demand for processed foods & energy drinks. Moreover, rapidly growing food & beverages industry in Asia Pacific countries including India, Malaysia, China & Indonesia and growing domestic demand for foods & beverages in emerging countries of BRICS are expected to boost the market growth in the upcoming period. In addition, the growing demand for soy proteins for food applications such as snacks, dairy products and sports nutrition will positively contribute to the growth of the protein ingredients market in the next couple of years.

However, fluctuating prices of protein-based products is negatively impacting the growth of protein ingredients industry. The market is widely analyzed based on different regional factors such as gross domestic product (GDP), demographics, acceptance, inflation rate and others. The market is categorized based on product type, form, application and geography. The market is classified into form such as isolate, concentrate and others.

North America is expected to hold the large market share in the upcoming period due to increasing consumption of energy bars, snacks & cold cereals, growing demand for high nutritional products, increasing disposable income, new product development, increasing the number of health conscious population and growing food & beverage industry. Asia Pacific is projected to grow at the higher CAGR in the years to come owing to growing exports and domestic demand. The growth of cosmetics & healthcare industries in India, Japan, South Korea and China, coupled with the low manufacturing cost of protein-based products as compared to the U.S. and European countries, is expected to boost the protein ingredients market growth in the upcoming period.

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The key players contributing to the robust development of the protein ingredients industry include DuPont, Archer Daniels Midland Company (ADM) Inc., Cargill Inc., Kewpie Corporation, Kerry Group plc, E. I. du Pont de Nemours and Company, Arla Foods, Bunge Limited, AMCO Proteins, Omega Protein Corporation, GELITA AG, Fonterra Co-operative Group Ltd., Hilmar Ingredients and CHS Inc. The major market players are focusing on inorganic growth to sustain themselves amidst fierce competition. As such, mergers, acquisitions, and joint ventures are the need of the hour.

Market Segment:

Protein Ingredients Type Outlook (Volume, Kilo tons; Revenue, USD Million; 2014 - 2025)
• Plant proteins
• Animal proteins

Plant Protein Ingredients Product Outlook (Volume, Kilo tons; Revenue, USD Million; 2014 - 2025)
• Wheat
• Soy protein concentrates
• Soy protein isolates
• Textured soy protein
• Pea
• Canola
• Others

Animal Protein Ingredients Product Outlook (Volume, Kilo tons; Revenue, USD Million; 2014 - 2025)
• Egg protein
• Milk protein concentrates/isolates
• Whey protein concentrates
• Whey protein hydrolysates
• Whey protein isolates
• Gelatin
• Casein/Caseinates

Protein Ingredients Application Outlook (Volume, Kilo tons; Revenue, USD Million; 2014 - 2025)
• Foods & beverages
• Infant formulations
• Personal care & cosmetics
• Animal Feed

Regional Outlook (Volume, Kilotons; Revenue, USD Million, 2014 - 2025)
• North America
• U.S.
• Europe
• UK
• Germany
• Asia Pacific
• China
• India
• Latin America
• Brazil
• Middle East & Africa

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