The global Sugar Substitutes Market is predicted to reach USD 19.1 billion in the forecast period owing to the growing customer’s preference towards the low-calorie foodstuffs. Sugar Substitutes are the chemical or plant-based constituents that sweeten the flavor of drinks and foods. They are also known as the “artificial sweeteners” or “non-caloric sweeteners” which are used as an ingredient in processed foods and drinks or as a tabletop sweetener like sweetening a glass of ice tea.

The sugar substitutes are sweeter than sugar, therefore small quantity of these substitutes offer greater level of sweetness. Most Sugar Substitutes are less in calorie or contain no calorie. The growing demand for low-calorie foodstuffs are projected to boost the sugar substitutes market significantly by 2024 with a CAGR of 4.2%. The demand for sugar substitutes is spurring across the globe. Especially in the beverage industry where the sweetness intensity varies from drink to drinks, sugar substitutes are extensively used. The market growth is driven by the factors like quality of the sugar substitutes, the mixture and content in processing foods, the standards enforced by local and international governments.

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One of the major drivers of the market is the rise in number of ventures pertaining to food industry. This is because the food industry is the main source of taste and has wide applications in medications too. The rising cost of raw material and the growing supply chain prices are expected to restrain the market in future. However, consumption of high content sugar foods leading to diabetes, heart disease and obesity is also increasing. Currently, people are adopting sugar-free products as a preventive measure for the growing health problems. Most health issues are found among people above 45 years of age and are expected to fuel the sugar substitute market in the coming years.

Stevia is a unique food ingredient, obtained from plants is best known for restricting the calories in the body. It is gaining demand in the European countries since it can be added to beverages as a sweetener in combination with sucrose. Strict safety standards is a major challenge for the sugar substitutes players. They are required to receive approvals from authorities like Foods Standard Agency before the launch of the product. The beverages and foods that contain artificial sweeteners must essentially follow the guidelines imposed by the regulatory bodies concerning the quantity sweeteners to be used, labeling, marketing and the daily average intake of sweeteners.

The sugar substitutes industry is segmented especially due to the existing of numerous large and small players that strengthen the competition for factors like quality, price, innovation, reputation, packaging, distribution and marketing channels. Such a penetrating competition among the players along with speedy technological variations is a key challenge that affects the operations of the players in the sugar substitutes industry. To stand successfully in such a competitive market, the vendors must distinguish themselves through USP (Unique Selling Proposition).

The sugar substitutes market is categorized on the grounds of product type, composition, application and geography. On the grounds of product type, the market is divided into High-intensity sweeteners, Low-intensity sweeteners and High-fructose syrups. On the grounds of composition, the industry is divided into High-intensity sweeteners and Low-intensity sweeteners. High-intensity sweeteners can be further classified as Stevia, As per tame, Cyclamate, Sucralose, Saccharin, Ace-K, and others. Low-intensity sweeteners can be further classified as D-Tagatose, Sorbitol, Maltitol, Xylitol, Mannitol, Erythritol and others. On the grounds of application, the sugar substitutes industry is divided as Beverages, Food (Confectionery, bakery, dairy and frozen foods) and Health & Personal Care.

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Geographically, the sugar substitutes market is sub-segmented as North America, Asia Pacific, Europe, Latin America and rest of the world (RoW). The speedy growth of consuming low-caloric food is observed especially in developing nations like Middle East, Asia-Pacific, Latin America, and Africa. This is predicted to drive the global market. This also results in rising focus of main sugar substitute manufacturers on offering superior quality and safe products with the help of advanced technologies. This is projected to affect the market in terms of quality and quantity.

The major players in the sugar substitutes industry are Cargill Incorporated, Tate & Lyle PLC, E. I. du Pont de Nemours and Company, Roquette Freres S.A., and Pure Circle Ltd., Ajinomoto Co. Inc., Archer Daniels Midland Company, MacAndrews & Forbes Incorporated, Ingredion Incorporation, and JK Sucralose Incorporation.

Market Segment:

Sugar Substitutes Product Outlook (Volume, Thousand Tons; Revenue, USD Million, 2013 - 2024)
    • High intensity sweeteners
    • Low intensity sweeteners
    • High fructose syrup

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The global Bone Grafts and Substitutes Market is set to grow at an exponential rate by the year 2025. Bone grafts are been increasingly used in oncologic revision prosthetic surgery, traumatology, bone regeneration, and spine surgery. Orthopedics over several years have used bone grafts and substitutes for assisting bone repair surgeries.

“Technological developments and trends such as stem cell and tissue engineering have demonstrated a huge potential for augmenting the prevailing performance of bone grafts. Alternatively, tissue engineering has made it possible to culture cells identical to the ones found in bone marrow.”

The market is majorly driven by the rising number of geriatric population all over the world. Ongoing technological advancements in the medical field has led to a significant shift from the use of autograft to allograft techniques. In addition, the growing cases of chronic lifestyle diseases like obesity and diabetes are estimated to further boost the market expansion.

In terms of bone graft and substitute type, the market has been segmented into allograft, demineralized bone matrix, bone morphogenic proteins or BMP, cell-based matrices, machined allograft, bone graft substitute, and synthetic bone grafts. By application, spinal fusion, joint reconstruction, dental bone grafting, trauma, and craniomaxillofacial are the primary classification of the market.

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Based on end-user industry, the global bone grafts & substitutes market has been categorized into orthopedic clinics, hospitals, and others. Allograft bone is generally collected from either nonliving donors or living donors (i.e. patients undergone whole hip replacement surgery) and must be administered for surgery within a bone tissue bank. The considerable rise in the number of bone tissue banks is driving the market for allograft substitute type industry.

In order to study the span of this industry, the global market has been geographically segmented into the five key regions of North America, Europe, the Asia Pacific, the Middle East, and Africa, and Latin America. The rise in disposable income and improving healthcare infrastructure is driving the bone draft and substitutes industry growth across the developing regions of Asia Pacific and Latin America. North America and Europe hold the largest market share attributed to the penetration of major players in these regions.

The competitive landscape of bone grafts and substitutes market encompasses an array of highly acclaimed contenders like Arthrex, Inc., Integra Life Sciences Holdings Corporation, Johnson & Johnson (DePuy Synthes), Musculoskeletal Transplant Foundation, Stryker Corporation, Wright Medical Group N.V., Baxter International Inc., Medtronic Plc., NuVasive, Inc., and Zimmer Biomet Holdings, Inc. among others. The altering market dynamics can be attributed to major merger and acquisition activities, collaborations and joint ventures amongst the industry competitors.

The emerging companies have identified raw material suppliers, buyers, research investors and distributors of the bone grafts and substitutes industry. The competitors are profiling their business expansion strategies by incorporating merger & acquisition, collaborations, and joint ventures with the fellow contenders.

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Over the past few years, considerable improvements have been made in order to realize significant implications for the future management of bone loss. Future developments have been projected to be focused on material composition for the delivery of BMPs, which has determined increased incorporation of stem cell technology. The ideal bone graft will have similar osteoinductive, osteoconductive and osteogenic characteristics as an autogenous bone. Considering the changing competitive dynamics and the current scenario of the industry, it has set the bone grafts & substitutes market to grow at an exponential rate during the forecast years.

Market Segment:

Bone Grafts and Substitutes Material Type Outlook (Revenue, USD Million, 2014 - 2025)
• Natural
• Autografts
• Allografts
• Demineralised Bone Matrix
• Others
• Synthetic
• Ceramic
• Composite
• Polymer
• Bone Morphogenetic Proteins (BMP)

Bone Grafts and Substitutes Application Type Outlook (Revenue, USD Million, 2014 - 2025)
• Spinal Fusion
• Dental
• Joint Reconstruction
• Craniomaxillofacial
• Foot and Ankle
• Long Bone

Bone Grafts and Substitutes Market Regional Outlook (Revenue, USD Million, 2014 - 2025)
• North America
• U.S.
• Canada
• Europe
• Germany
• U.K.
• Asia Pacific
• Japan
• China
• Latin America
• Mexico
• Brazil
• MEA
• South Africa