Annalice, a single mother and physician, is ready to immerse herself in the mundane chores of her farm as a diversion from her hectic professional life. But she becomes the victim of a home invasion, the supernatural kind. Vindictive and cruel, Asa, a century old vampire, takes brutal control of her life and home. Forcing her to strike a bargain in exchange for her daughter's life, Annalice must not only accept his presence but also bow to his depravity. Facing threats to her only child, she relies on her skills as a physician to unravel the clues to the vampire's existence attempting to beat him at his own game. Caught in a race against a genetic timeline, Annalice struggles to survive the Blood Reaction.