An epidemic that turns men into monsters has seized the nation. At first the disease only spreads in cities but soon cannibals are roaming the prairie, threatening the quiet little towns of the late 19th Century heartland. At an isolated poor farm in rural America, Sara Warren has survived a tumultuous life of loss and an accident that leaves her with one leg – but she is hopeless of any other future until a woman named Cordelia arrives at the farm and changes Sara's life forever. Along with Dan, a man who can't hear and Grace, a young woman who is more concerned with her sewing needles than people, they face the oncoming apocalypse with their wits and their bare hands. When it seems like all is lost, a man from Sara's past named Jack returns to her life and they all realize the only way to survive is together. A story of romance, violence, sex, and the wild prairie that proves broken bodies still feel pleasure and broken souls can find love – even at the end of the world.