Adriana Sinclair is an evolutionary mystery. Her blood type matches nothing in modern medicine. When a failed blood transfusion kills her twin sister, Adriana discovers she's a throwback to an original human that geneticists have coined the “Mitochondrial Eve.”

Adriana is shocked to learn her strange blood type is her family’s most protected secret. Working with spotty clues and partial facts, Adriana is determined to find the truth.

Still reeling from her sister's death and the subsequent realization of her family’s secret, Adriana struggles to put her life back in order and focus on her college studies. She finds comfort in Kalan, the new guy whose striking albino features and friendly manner keep her distracted from the wreck her life has become. Kalan is exactly what she needs right now, even if he does seem a bit too interested in Adriana's mysterious bloodline...