This volume summarizes the historical background and the biological and pathophysiological aspects of heat interaction with radiotherapy and chemotherapy and presents the technical state of the art of the combination of radiotherapy and/or chemotherapy with hyperthermia. The book will appeal to theoretical researchers in biology, physiology, physics, and engineering and to oncological practitioners and specialists in related areas. The complementary volume 2 (to be published in October 1995) focuses on clinical practice and the results which have been achieved with combined thermoradiotherapy and thermochemotherapy for various tumors. Special applications such as intracavitary, interstitial, intraoperative and whole-body hyperthermia, are addressed in detail.