A new year and new decade have just begun. People use the opportunity to set new goals including leading a healthier lifestyle. Here are some tips to start the year on a healthier note. The best doctors in Ahmedabad can suggest some blood test on regualr basis, you can book best diagnostic test in Ahmedabad.

• We should incorporate a balanced meal as a part of our diets. Fruits, vegetables, legumes, nuts, and whole grains should be included in every meal. Eating healthier prevents malnutrition and reduces the risk of diseases such as diabetes, heart disease, stroke, and cancer. 

•  Excessive sodium intake is linked to high blood pressure which increases the risks of stroke or heart diseases. Salt is the primary source of sodium. Sodium is essential for our bodies to functioning as it helps to maintain the balance of fluids in our body, transmitting nerve impulses, and normal cell function. Limiting the amount of salt in meals, using high salt condiments, and avoiding high salt snacks can help you lower your salt intake,

Tooth decay, type 2 diabetes, heart disease, cancer, and weight gain has been linked to excess sugar consumption. Sugar is found naturally in several fruits and vegetables. This sugar is not harmful and is healthy. Added sugar in processed foods is unhealthy. Reducing your consumption of sugar-filled drinks and desserts can bring down processed sugar intake.

• Fat consumed should be less than 30% of your energy intake. This will prevent unhealthy weight gain and reduce the risk of “lifestyle disease”. Unsaturated fats found in nuts and some oils are preferable to saturated-fats and trans-fats.

•  Smoking is linked to various diseases such as lung and heart diseases, cancer, and stroke. It affects both smokers and passive smokers. People who give up smoking experience immediate and long-term health benefits. 

Excessive alcohol consumption can cause health problems and mental and behavioral disorders.  It has also been linked to liver cirrhosis, cancers, and heart diseases. You should drink moderately if you drink alcohol.

• Experts suggest adults should do at least 150 minutes of moderate-amount physical activity, throughout the week. Increasing it to 300 minutes per week will increase your health benefits.

• Vaccination is one of the most effective ways to prevent diseases such as cervical cancer, cholera, diphtheria, hepatitis B, influenza, measles, and mumps. Consult the best doctors in Ahmedabad to get more information about vaccines. It is important not to miss the vaccination schedule for your child.

• Hypertension or high-blood-pressure is called a “silent killer”. Doctors have linked it to heart, brain, and kidney diseases. Having your blood pressure checked regularly by the best doctor near me can help you prevent or control hypertension.

• Depression is a common illness and can make you feel hopeless and worthless. In case you are depressed, talk to someone you trust or consult a counselor or physiologist. 

• Antibiotic-resistant bacteria is becoming a serious health threat. Antibiotics are becoming less potent because of misuse and overuse. It is important to have antibiotics only when prescribed by the best doctor in Ahmedabad. You should complete the required course of the antibiotics. 

• Cleaning your hands regularly can prevent the spread of diseases.

•  Regular checkups with the best orthopedic doctor near me is a great way to find health problems before they start. Early diagnosis is the key to prevent many illnesses. 

Tuberculosis or TB is caused by bacteria (Mycobacterium Tuberculosis) that affects the lungs. The infection can spread to other parts of your body like the brain or spine.  TB is an infectious disease which spreads when an infected person coughs, sneezes or spit. TB is curable and preventable. We can cure most cases of TB with antibiotics but you need to take the medication for 6 to 9 months. Without treatment two-thirds of infected patients will die. An antioxidant found in green has shown a lot of promise in tackling the dreaded disease. A team of scientists from the Nanyang Technology University in Singapore has spearheaded the research.

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Laboratory experiments led by Professor Gerhard Grüber discovered a compound called epigallocatechin gallate (EGCG), which can slow down the growth of Mycobacterium Tuberculosis bacteria.

The EGCG does this by binding to the enzyme responsible for biological energy for cellular activity.  These results in a dip in energy the bacteria have for growth and stability. It published the finding in the Scientific Reports. There is hope the findings can help create drugs to combat tuberculosis.

Southeast Asia accounts for 41% of the world’s tuberculosis cases. According to the World Health Organization, India has the largest number of TB cases in the world. There were over 2.7 million cases of TB in 2018. While there are many drugs already available in the market to combat the disease, we need new ones because the bacteria are showing resistance to many drugs. 

According to Professor Gerhard Grüber from the NTU School of Biological Sciences said: “Though tuberculosis is curable, the success of current drugs on the market is increasingly being overshadowed by the bacteria’s clinical resistance. Our discovery of the EGCG’s ability to inhibit the growth of M. tuberculosis will allow us to look at how we can improve the potency of this compound in green tea, and other similar compounds, to develop new drugs to tackle this airborne disease.”

How does EGCG work?

Cells need energy for processes such as cell wall formation they get their energy from an energy storage molecule containing an enzyme called ATP synthase. Without energy for crucial cellular activity, the cell becomes unstable and dies.

To determine the features affection production of ATP synthase, the NTU research team studied both Mycobacterium smegmatis and Mycobacterium Bovis, both of which were from M.Tuberculosis family. They have similar structural composition.

The team found that if genetic code for ATP synthase was altered it resulted in few energy storage molecules in bacterial cells, retarded cell growth and a changed colony shape.

Armed with this data, the scientists tested over 20 compounds to find something to bing to ATP synthase and cause the same blocking effect and tested their efficiency. Only EGCG, an antioxidant found in green tea showed positive results.

The team led by Professor Gerhard Grüber is developing the activity of EGCG for increased effectiveness and strength to fight the M. Tuberculosis bacteria. They hope to develop a drug cocktail that will effectively fight multi-drug resistant tuberculosis.

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