The pancreas is a large organ, about six inches long situated in the abdomen, behind the stomach which is a crucial component of the digestive process. The organ is divide into three regions namely the head, the body and the tail. Pancreas have two functional parts, exocrine and endocrine. creates hormones like insulin which help control blood sugar, also enzymes that help in the break- down of food in the small intestine.

Pancreatic cysts

Pancreatic cysts are fluid collections that form within the head, body and tail of the pancreas. It can be divided into two groups, neoplastic and non- neoplastic. Each group includes many different subtypes of cysts, such as pseudo cysts, serous cystadenomas and mucinous cystic neoplasms. Some pancreatic cysts can be or can become cancerous.

Causes of Pancreatic cysts

There is no defined cause of pancreatic cysts and so it is usually unknown. While some cysts are associated with rare illness, including polycystic kidney disease or von Hippel- Lindau disease which is a genetic disorder that affect the pancreas and other organs.

While in case of Pseudo cysts, it often follows a bout a painful condition in which digestive enzymes become prematurely active and irritate the pancreas. It can also result due abdomen injury.

Symptoms of Pancreatic cysts

Pancreatic cysts symptoms vary depending on their size and location. Small cysts which are less than two centimetre, tend to show no symptoms. While, large cysts apparently cause abdominal pain and back pain by exerting pressure on the surrounding nerves and tissues. Cysts in the head of the pancreas can cause jaundice, which is yellowing of the skin and eye with darkening of the urine. Jaundice is caused due to the obstruction of the common bile duct. In case if the cysts become infected then it may result in fever, chills and sepsis. Occasionally, large pseudo cysts can compress the stomach or the duodenum leading to obstruction to the movement of food in the intestines which will result in abdominal pain and vomiting. A formation of malignant cyst, will begin to invade the surrounding tissues which may lead to pain as that of pancreatic cancer that is felt in the back and upper abdomen. Some of the typical or common symptoms include nausea, vomiting, weight loss and feeling full soon after beginning to eat.

Diagnosis of Pancreatic cysts

Usually, improved imaging testing and abdominal scanning are used to diagnose the pancreatic cysts. But, imaging tests are recommended after briefing through medical history of a patient along with some physical exams. Some of the tests include, computerised tomography (CT) scan through which detailed information about the size and structure of a pancreatic cyst can be provided. MRI scan will highlight the information of a pancreatic cyst regarding any component that suggest any risk of cancer. An endoscopic ultrasound can provide detailed image of cyst also; fluid can be collected from the cyst for analysis of cancer signs in a laboratory.

Treatment for Pancreatic cysts

Method of treatment is recommended after the determination of whether a cyst is benign or cancerous. Usually precancerous or cancerous cysts are removed through surgical means. Buy medicines, health products online so as to avoid travelling after surgery. In case of pseudo cyst which is causing bothersome symptoms can be drained by passing a small flexible tube or endoscope through the moth to stomach and to small intestine. The endoscope is equipped with an ultrasound probe and a needle to drain the cyst. Medication is prescribed along with the above treatment. Best healthcare service provider in India should be approached to get information on the patient’s condition and health status, as decisions ought to be individualized

Prevention of Pancreatic cysts

Avoid pancreatitis, which is usually caused by gallstones or heavy alcohol use, to avoid pseudo cysts. The pancreatitis are triggered by gallstones then, removal of them is a best preventive measure. In case, if pancreatitis is due to consumption of alcohol then preferably stop drinking to reduce the possibility or risk of the disease.

So, visit a doctor when you a fever and persistent abdominal pain as one may not able to understand cysts infection very early. A medical emergency like ruptured pancreatic cyst, is fortunately rare. Therefore, get tested soon of any relatable symptoms and maintain good health status.

Market Overview:

The global market for artificial pancreas device system, as described by Market Research Future (MRFR), is showing potential of achieving almost 21.10% CAGR during the forecast period of 2018 to 2023. In the process, the market is showing promising signs of crossing USD 341.08 million by the end of 2023.

In case of type 1 and type 2 diabetes, the pancreas produces little to no insulin which makes it imperative for patients, especially those suffering from type 1diabetes, to inject insulin to regulate their blood glucose levels. This is important to keep complications such as cardiovascular disease, kidney failure, blindness etc. at bay. However, diabetes management involves blood glucose monitoring, insulin dose calculation and insulin infusion with needle or pump. The use of an artificial pancreas device system which continuously monitors blood glucose is often found to be beneficial for many patients. Healthcare regulatory bodies like the U.S. FDA are closely collaborating with academic investigators, diabetes patients, and care providers to develop innovative devices that will add impetus to the growth of artificial pancreas device system market.

The Artificial Pancreas Device System Market Growth is banking on technological support from the latest innovations, continuous rise in investment, better integration of innovations in the system, rising availability of skilled hands to support such processes, growing expenditure capacity, and others can impact the market for artificial pancreas device system. Growing awareness regarding diseases triggering the intake of the process can influence market growth.

Competitive Landscape:

• Bigfoot Biomedica
• Medtronic Plc
• Dexcom Inc
• Johnson & Johnson
• Tandem Diabetes Care Inc.
• Cellnovo
• TypeZero Technologies LLC
• Pancreum Inc
• Inreda Diabetic B.V.
• Beta Bionics
• Hoffmann-La Roche Ltd
• Insulet Corp

Segmentation:

• The segmentation, as covered by MRFR for their elaborate research of the market for artificial pancreas device system, can be taken into consideration for a better understanding of the market. These segments can portray the factors in a better way. This segmentation includes type and end-user.
• By type, the market for artificial pancreas device system can be segmented into CTT (Control To Target) Systems and CTR (Control to Range) Systems. Both these segments can impact the market profoundly.
• By end users, the market report for artificial pancreas device system covers several significant aspects of hospitals and medical centers.

Regional Analysis:

North America’s prospect in the global artificial pancreas device market is quite substantial. This is due to their immense technological integration, better understanding of the market benefits, strong health policies, better infrastructure, high capacity for investments, and others. Better awareness regarding various diseases can also play a positive role in taking the global market for artificial pancreas device system ahead. South America would witness growth in countries like Argentina, Brazil, Colombia, and others. However, their growth rate would not match that of North America’s where the US and Canada would significantly contribute.

Europe’s market would be substantially big due to the presence of market players in their top form and revamped financial situations in countries like France, Germany, and the UK. In several countries, government expenditure for research and healthcare can make sure that the market finds better growth structure in the coming days.

With increasing number of people suffering from diabetes, managing and controlling diabetes has become critical. Hence being user-friendly and portable, artificial pancreas systems are gaining popularity across the globe. Ensuring the effectiveness and safety of medical devices, the Food and Drug Administration (FDA) is helping in the development of innovative artificial pancreas system device. FDA is also making it sure that the device monitors blood glucose level automatically and provide proper insulin doses. However, along with basic features, manufacturers are also trying to develop high-end artificial pancreas systems to improve diabetes management.

According to the report by Mindaspire Market Research (MAMR), type 1 diabetes is estimated to exceed $250 million by 2026 in Europe and North America artificial pancreas systems market. It is also anticipated to increase to 12.9% CAGR during 2016-2026. While type 2 diabetes is expected to register 4.1% CAGR between 2016 and 2026 in artificial pancreas systems market in Europe and North America. Conventional CGM devices and insulin pumps are large in size, hence people are opting for artificial pancreas systems.

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North America and Europe artificial pancreas systems market: segmentation:

By Distribution Channel: Hospitals; E-Commerce;  By Disease Indication: Diabetes Type 1, Diabetes Type 2; By Region: North America, Western Europe, Eastern Europe

Emerging technologies to offer better artificial pancreas systems

Manufacturers are focusing on developing smaller, more reliable and streamlined artificial pancreas systems. For instance, Cellnovo, a France-based mobile diabetes firm recently raised €17.5 million to develop fully automatic artificial pancreas. The company is focusing on introducing a system that can measure glucose level and provide the right amount of insulin without input from humans. These fully automated artificial pancreas are expected to also reduce long-term complications associated with diabetes.

Companies are also entering into partnerships to develop and test artificial pancreas systems. For example, Roche, a pharmaceutical and medical device company has joined hands with Senseonics and TypeZero to develop a long term artificial pancreas automated system and conduct clinical trials of the system. Companies are developing artificial pancreas also referred as a closed loop diabetes management system. The new system would include insulin injection and glucose monitoring through algorithms. The system will also include Roche’s Accu-check insight insulin pump. A system including CGM sensor, lasting up to 90 days, smart algorithms and a discreet insulin pump is first of its kind.

Artificial pancreas for children

With increasing cases of diabetes among children, especially type 1 diabetes, manufacturers are also introducing artificial pancreas systems for children. Medtronic, a Minnesota-based medical device company has developed MiniMed 670G system for children suffering from type 1 diabetes. The system was also approved by FDA. This system includes a sensor to monitor glucose level in fluids under the skin, and based on the levels the device delivers and provide insulin.

Technological Advancements to Boost Artificial Pancreas Systems

Manufacturers of artificial pancreas systems are focusing on treating type 1 diabetes, in which pancreas produces very little or no insulin. According to the American Diabetes Association, type 1 diabetes patients are not more than 10%.

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While a recent study has also shown that artificial pancreas can better control condition of children with type 1 diabetes. The study found that children with artificial pancreas had lower average blood sugar level and they were more within the normal blood sugar range, without an increase in low blood sugar or hypoglycemia.

One of the largest company in North America & Europe’s artificial pancreas systems market has been identified as Illinois-based medical device manufacturer – Medtronic plc. With it, the UK-based Cellnovo is also being recognised as a prominent manufacturer of artificial pancreas systems. Other key players in the artificial pancreas systems market across North America and Europe include, Johnson & Johnson Services, Inc., Dexcom Inc., Insulet Corporation, and Tandem Diabetes Care IncLinco Baby Merchandise Works Co., Ltd.